Karstula is a municipality of Finland founded in 1867. It is located in the Central Finland region. The municipality has a population of 3,572 (31 October 2024) and covers an area of 963.19 square kilometres (371.89 sq mi) of which 76.22 km2 (29.43 sq mi) is water. The population density is 4.03 inhabitants per square kilometre (10.4/sq mi).
Neighbouring municipalities are Kannonkoski, Kivijärvi, Kyyjärvi, Saarijärvi and Soini.
There are all together 159 lakes in Karstula. Biggest lakes are Pääjärvi, Enonjärvi and Vahanka.