Isokyrö (Finnish: [ˈisoˌkyrø]; Swedish: Storkyro) is a municipality of Finland. It is located in the South Ostrobothnia region, 43 kilometres (27 mi) from Vaasa. The municipality has a population of 4,331 (31 August 2024) and covers an area of 356.91 square kilometres (137.80 sq mi) of which 2.79 km2 (1.08 sq mi) is water. The population density is 12.23 inhabitants per square kilometre (31.7/sq mi).
In the name of the municipality, "iso" means big; "kyrö", on the other hand, is a Tavastian dialect and means a quarry, rocky or rugged terrain for hiding. The municipality is unilingually Finnish.
According to Traficom, Isokyrö is the most motorized municipality in Finland with 718 cars per thousand inhabitants.